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BGT226 free base
CAS No. 915020-55-2
BGT226 free base ( NVP-BGT226 )
Catalog No. M24960 CAS No. 915020-55-2
Bgt226 is a novel dual PI3K / mTOR inhibitor, it acts on PI3K α/β/γ with IC50 of 4 nM / 63 nM / 38 nM, respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 104 | In Stock |
|
| 10MG | 177 | In Stock |
|
| 25MG | 390 | In Stock |
|
| 50MG | 574 | In Stock |
|
| 100MG | 803 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameBGT226 free base
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NoteResearch use only, not for human use.
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Brief DescriptionBgt226 is a novel dual PI3K / mTOR inhibitor, it acts on PI3K α/β/γ with IC50 of 4 nM / 63 nM / 38 nM, respectively.
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DescriptionBgt226 is a novel dual PI3K / mTOR inhibitor, it acts on PI3K α/β/γ with IC50 of 4 nM / 63 nM / 38 nM, respectively.
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SynonymsNVP-BGT226
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PathwayPI3K/Akt/mTOR signaling
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TargetPI3K
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RecptorPI3Kα; PI3Kβ; PI3Kγ; mTOR
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Research Area——
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Indication——
Chemical Information
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CAS Number915020-55-2
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Formula Weight534.5
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Molecular FormulaC28H25F3N6O2
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Purity>98% (HPLC)
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Solubility——
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SMILESCN(c(cnc(c1c2)ccc2-c(cc2)cnc2OC)c1N1c(cc2)cc(C(F)(F)F)c2N2CCNCC2)C1=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Markman B , Tabernero J , Krop I , et al. Phase I safety, pharmacokinetic, and pharmacodynamic study of the oral phosphatidylinositol-3-kinase and mTOR inhibitor BGT226 in patients with advanced solid tumors[J]. Annals of Oncology Official Journal of the European Society for Medical Oncology, 2012, 23(9):2399.
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BGT226 free base
Bgt226 is a novel dual PI3K / mTOR inhibitor, it acts on PI3K α/β/γ with IC50 of 4 nM / 63 nM / 38 nM, respectively.
